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Fig. 1 | Intensive Care Medicine Experimental

Fig. 1

From: Critical role of endogenous histamine in promoting end-organ tissue injury in sepsis

Fig. 1

Changes in histamine synthesis and histamine receptor expression in lung, liver, and kidney tissues from mice after CLP-induced sepsis. a Tissue histamine concentrations after CLP (n = 8/group). b Tissue mRNA levels of HDC, histamine H1- and H2-receptors after CLP (n = 6/group). The mRNA levels were quantified by real-time PCR. The values were expressed as a fold increase above control normalized GAPDH. All values are provided as means ± SEM. *P < 0.05, **P < 0.01, and ***P < 0.001 vs. control

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