Resuscitation fluid composition affects hepatic inflammation in a murine model of early sepsis

Intensive Care Medicine Experimental

Table 1 Constituents of novel balanced crystalloid solutions

Compound	Mass (g/L)	Ion	Concentration (mmol/L)
A) Seplyte L (low acetate, no potassium)
MgCl₂	0.119	Na⁺	142
CaCl₂	0.277	Cl⁻	103
NaCl	5.581	Mg²⁺	1.25
NaC₆H₁₁O₇ (sodium gluconate)	4.035	C₆H₁₁O₇ ⁻	18.5
NaCH₃CO₂ (sodium acetate)	2.297	CH₃COO⁻	28
NaCH₃CO₂ (sodium acetate)	2.297	Ca²⁺	2.5
B) Seplyte H (high acetate, no potassium)
MgCl₂	0.119	Na⁺	142
CaCl₂	0.277	Cl⁻	103
NaCl	5.611	Mg²⁺	1.25
NaC₆H₁₁O₇ (sodium gluconate)	2.618	C₆H₁₁O₇ ⁻	12
NaCH₃CO₂ (sodium acetate)	2.789	CH₃COO⁻	34
NaCH₃CO₂ (sodium acetate)	2.789	Ca²⁺	2.5