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Table 3 Mean absolute systemic leukocyte counts (±SEM) in response to resuscitation fluid treatment in C57BL/6 mice undergoing sham or CLP surgery

From: Resuscitation fluid composition affects hepatic inflammation in a murine model of early sepsis

Fluid type

Sham (×109 cells/L)

CLP (×109 cells/L)

A) Neutrophils

 Ringer’s lactate

1.22 ± 0.18

0.35 ± 0.04*

 Normal saline

1.66 ± 0.15

0.39 ± 0.06*

 Normal saline + 5% albumin

2.69 ± 0.17

0.90 ± 0.22*

 Seplyte L

1.63 ± 0.11

0.46 ± 0.11*

 Seplyte L + 5% albumin

1.83 ± 0.16

0.20 ± 0.05*^

 Seplyte H

2.08 ± 0.15

0.68 ± 0.24*

 Seplyte H + 5% albumin

1.08 ± 0.23

0.53 ± 0.14

B) Lymphocytes

 Ringer’s lactate

2.20 ± 0.18

1.60 ± 0.26

 Normal saline

1.83 ± 0.17

1.76 ± 0.15

 Normal saline + 5% albumin

1.61 ± 0.22

1.44 ± 0.16

 Seplyte L

1.65 ± 0.08

1.92 ± 0.31

 Seplyte L + 5% albumin

1.78 ± 0.16

2.56 ± 0.38

 Seplyte H

1.49 ± 0.22

2.22 ± 0.38

 Seplyte H + 5% albumin

1.08 ± 0.22

1.50 ± 0.21

C) Monocytes

 Ringer’s lactate

0.23 ± 0.03

0.07 ± 0.01*

 Normal saline

0.27 ± 0.05

0.13 ± 0.03*

 Normal saline + 5% albumin

0.19 ± 0.04

0.10 ± 0.03

 Seplyte L

0.32 ± 0.06

0.16 ± 0.03*

 Seplyte L + 5% albumin

0.28 ± 0.10

0.06 ± 0.26

 Seplyte H

0.14 ± 0.05

0.15 ± 0.03

 Seplyte H + 5% albumin

0.18 ± 0.06

0.05 ± 0.02

  1. *p < 0.05 compared to sham, ^p < 0.05 compared to normal saline + 5% albumin CLP