Proliferation and differentiation of adipose tissue in prolonged lean and obese critically ill patients

Intensive Care Medicine Experimental

Table 2 Baseline and outcome characteristics of matched critically ill patients of whom serum samples were used in the in vitro study

	Lean critically ill (N = 20)	Overweight/obese critically ill (N = 20)	p value^c	Healthy reference (N = 47)	p value^d
Baseline characteristics
Gender (n, % male)	13 (65)	12 (60)	0.9	30 (64)	1
BMI, kg/m² (mean ± SEM)	22.4 ± 0.4	29.3 ± 0.9	<0.0001	24.8 ± 3.6	0.2
Age, years (mean ± SEM)	57.2 ± 3.8	56.9 ± 3.4	0.4	58 ± 2.4	0.7
APACHE II score (mean ± SEM)	18.6 ± 6	19.3 ± 6.3	0.6
Diagnostic admission category (n)	2	3	0.6
Cardiac surgery	2	1
Complicated surgery^a	3	5
Multiple trauma or burns	3	3
Hematologic or oncologic	4	1
Respiratory	4	6
Other disease exacerbations^b	2	1
Other sepsis
Received steroid therapy (n, %)	0 (0)	0 (0)	1

SEM standard error of the mean, BMI body mass index
^aComplicated surgery indicates patients suffering from complications after abdominal or pelvic surgery, pulmonary or esophageal surgery, or vascular surgery
^bCardiovascular disease, gastroenterologic or hepatic disease, neurologic disease
^cComparison between lean and overweight/obese critically ill patients
^dComparison between critically ill patients and healthy references