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Table 1 Physiological data

From: Cardiovascular disease and resuscitated septic shock lead to the downregulation of the H2S-producing enzyme cystathionine-γ-lyase in the porcine coronary artery

  

Baseline

24 h

NoA (μg/(kg min))

Sham

0.06 (0.02; 0.13)

Sepsis

1.23 (0.66; 3.26)a

Mean arterial pressure (mmHg)

Sham

100 (90; 106)

103 (94; 119)

Sepsis

103 (91; 112)

65 (61; 81)a, b

Central venous pressure (mmHg)

Sham

8 (7; 13)

10 (9; 15)b

Sepsis

10 (6; 13)

17 (14; 18)b

Cardiac output (ml/(kg min))

Sham

61 (52; 79)

64 (42; 92)

Sepsis

64 (52; 69)

87 (62; 130)b

pO2 (mmHg)

Sham

158 (142; 180)

159 (138;177)

Sepsis

170 (161; 183)

93 (62; 155)a, b

pCO2 (mmHg)

Sham

35 (35; 39)

35 (33; 36)

Sepsis

38 (34; 40)

35 (32; 44)

arterial pH

Sham

7.46 (7.44; 7.46)

7.44 (7.43; 7.46)

Sepsis

7.45 (7.43; 7.48)

7.37 (7.19; 7.43)a, b

Lactate (mmol/l)

Sham

1.4 (1.0; 1.6)

0.6 (0.6; 1.2)

Sepsis

0.8 (0.6; 1.5)

6.1 (2.0; 10.7)a, b

Base excess (mmol/l)

Sham

1.1 (0.8; 1.8)

−0.1(−1.45; 0.65)

Sepsis

1.5 (0.4; 2.3)

−8.5 (−14.6; −3.7)a, b

  1. Physiological data, presented as median (interquartile range, IQR). Sham n = 5, sepsis n = 8
  2. NoA norepinephrine infusion rate, pO 2 partial oxygen pressure, pCO 2 partial carbon dioxide pressure
  3. aSignificant compared to sham
  4. bSignificant compared to baseline