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Table 1 Prospective validation in pigs

From: Ultra-low-dose sequential computed tomography for quantitative lung aeration assessment—a translational study

CT Variable

Spiral, 180 mAs

Sequential, 20 mm feed, 180 mAs

Sequential, 20 mm feed, 50 mAs

Analysis results

Analysis results

ρ

Bias (LOA)

Analysis results

ρ

Bias (LOA)

Total lung volume (ml)

1184 (1143–1244)

1168 (1140–1270)

0.867

2 (−64–69)

1185 (1156–1286)

0.839

10 (−62 to 82)

Total lung weight (g)

665 (598–681)

650 (581–672)

0.902

−10 (−59–39)

658 (593–683)

0.727

−2 (−65 to 61)

Hyper-aerated tissue (%)

0.2 (0.1–0.4)

0.3 (0.1–0.5)

0.993

0.1 (−0.3–0.5)

0.3 (0.2–0.5)

0.993

0.2 (−0.4 to 0.7)

Normally aerated tissue (%)

26.8 (23.6–38.8)

27.4 (24.9–37.8)

0.986

0.4 (−2.7–3.5)

26.8 (23.3–36.9)

0.993

−0.1 (−3.0 to 2.7)

Poorly aerated tissue (%)

41.7 (32.9–45.6)

39.0 (30.2–45.1)

0.972

−1.9 (−4.9–1.1)

39.6 (30.5–45.3)

0.965

−1.8 (−5.6 to 2.1)

Non-aerated tissue (%)

29.3 (18.2–34.3)

30.0 (18.0–34.7)

0.972

1.4 (−3.3–6.1)

30.3 (18.6–35.8)

0.874

1.7 (−3.1 to 6.5)

  1. Comparison between CT analysis performed on the reference spiral scan and extrapolated from the two sequential scan protocols. ρ is Spearman’s rank correlation between extrapolated variables and the reference ones. Data are medians (interquartile ranges). Bias (LOA) is the result of the Bland–Altman analysis, reported as bias (limits of agreement)