Fig. 7
From: Improving animal welfare using continuous nalbuphine infusion in a long-term rat model of sepsis
Nalbuphine plasma levels. Nalbuphine plasma levels at 15 min (sham nalbuphine, n = 6), 4 h (sepsis nalbuphine, n = 6) and 24 h (sepsis nalbuphine, n = 4). Samples were obtained from independent animals without repeated blood sampling (one-way ANOVA p < 0.001). Post-hoc test revealed significantly higher plasma levels at 4 h (§: p = 0.002) and 24 h (£: p < 0.001) vs 15 min. There was no significant difference between 4 and 24 h