Skip to main content
Fig. 3 | Intensive Care Medicine Experimental

Fig. 3

From: The role of high airway pressure and dynamic strain on ventilator-induced lung injury in a heterogeneous acute lung injury model

Fig. 3

The effect of both high (OD + H DS ) and low (OD + L DS ) dynamic strain on total protein concentration, matrix metalloproteinase-9 (MMP-9) activity, and both surfactant protein A (SP-A) and B (SP-B) levels in bronchoalveolar lavage fluid (BALF) of normal (N T ) and acutely injured (ALI T ) lung tissue. a Low dynamic strain (OD + LDS) prevented the increase in total protein in normal lung tissue (NT). b Low dynamic strain (OD + LDS) prevented the increase in MMP-9 activity in NT. c High dynamic strain (OD + HDS) caused a decrease in SP-A in NT. d No differences in SP-B were seen with high or low dynamic strain or in normal or acutely injured lung tissue. Data mean ± SD

Back to article page