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Fig. 2 | Intensive Care Medicine Experimental

Fig. 2

From: Effect of continuous dialysis on blood pH in acidemic hypercapnic animals with severe acute kidney injury: a randomized experimental study comparing high vs. low bicarbonate affluent

Fig. 2

Temporal metabolic determinants of SBE variation based on group. Panel a shows the SID changes over time (mixed model: group vs. SIDa interaction, P = 0.021; timepoint vs. SIDa interaction, P < 0.001; timepoint vs. group interaction, P < 0.001). Panel b shows the SIG changes over time (mixed model: group vs. SIG interaction, P = 0.483; timepoint vs. SIG interaction, P = 0.797; timepoint vs. group interaction; P = 0.364). Panel c shows the lactate changes over the time (mixed model: group vs. lactate interaction, P = 0.473; timepoint vs. lactate interaction, P = 0.936; timepoint vs. group interaction, P = 0.871). Panel d shows the albumin changes over time (mixed model: group vs. albumin interaction, P = 0.182; timepoint vs. albumin interaction, P = 0.833; timepoint vs. group interaction, P = 0.432). Panel e shows the phosphate changes over time (mixed model: group vs. phosphate interaction, P = 0.565; timepoint vs. phosphate interaction, P = 0.450; timepoint vs. group interaction, P = 0.531). SID denotes strong ion difference. SIG denotes strong ion gap. SBE denotes standard base excess. *Wilcoxon post hoc analysis, P < 0.05 vs. baseline. $Mann-Whitney post hoc analysis, P < 0.05 vs. group 40

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