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Intensive Care Medicine Experimental
Fig. 4 | Intensive Care Medicine Experimental

Fig. 4

From: Effect of continuous dialysis on blood pH in acidemic hypercapnic animals with severe acute kidney injury: a randomized experimental study comparing high vs. low bicarbonate affluent

Fig. 4

Temporal changes of CO2 content over RRT. Panel a shows the venous CO2 content evolution over the time (mixed model: group vs. venous CO2 content interaction, P = 0.230; timepoint vs. venous CO2 content interaction, P < 0.001; timepoint vs. group interaction, P < 0.001). Panel b shows the arterial CO2 content changes over time (mixed model: group vs. arterial CO2 content interaction, P = 0.231; timepoint vs. arterial CO2 content interaction, P < 0.001; timepoint vs. group interaction, P < 0.001). Panel c shows the venous-arterial CO2 gradient changes over time (mixed model: group vs. venous-arterial CO2 gradient interaction, P = 0.815; timepoint vs. venous-arterial CO2 gradient interaction, P = 0.919; timepoint vs. group interaction, P = 0.972). Panel d shows the effluent CO2 content changes over time (mixed model: group vs. effluent CO2 content interaction, P = 0.769; timepoint vs. effluent CO2 content interaction, P = 0.136; timepoint vs. group interaction, P = 0.242), for the effluent CO2 content, the baseline data were excluded. *Wilcoxon post hoc analysis, P < 0.05 vs. baseline

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