Fig. 4

Renal oxygen consumption (QO₂, a) and renal QO₂ per reabsorbed sodium (b) in 16 sheep subjected to renal ischemia and reperfusion. Renal ischemia was caused by clamping of the renal artery for 90 min. Fifteen minutes prior to the release of the clamp intravenous treatment with either 1,2-propanediol nitric oxide (PDNO, n = 8) or vehicle (propanediol + inorganic nitrite, n = 8) was commenced. The treatment continued for 6 h. Data are expressed as mean and SEM. Significant (p < 0.05) differences in response to PDNO compared to vehicle is indicated by an asterisk