Table 2 Predictive value of laboratory tests assessed at admission for sepsis development during ICU stay
Variable | Development of sepsisa | P valueb | |
|---|---|---|---|
No (N = 80) | Yes (N = 19) | ||
Routine | |||
CRP (mg/L) | 14.1 ± 37.7 | 29.1 ± 61.7 | 0.053 |
Fibrinogen (g/L) | 2.6 ± 0.99 | 3.3 ± 2.0 | 0.11 |
PTT (s) | 14.4 ± 1.7 | 14.4 ± 3.3 | 0.78 |
Prothrombin Time Index (%) | 66.3 ± 15.6 | 69.7 ± 19.4 | 0.61 |
Platelet count (103/μL) | 124 ± 55 | 133 ± 84 | 0.59 |
d-dimers (μg/L) | 2617 ± 6353 | 4456 ± 4957 | 0.0032 |
ISTH score | 1.6 ± 1.3 | 2.6 ± 0.9 | 0.041 |
White blood cell count (103/μL) | 10.0 ± 4.4 | 11.1 ± 5.2 | 0.42 |
Flow cytometry | |||
TNF-α (pg/mL) | 0.17 ± 0.8 | 0.65 ± 1.5 | 0.091 |
IL-10 (pg/mL) | 19.4 ± 90 | 9.4 ± 16.2 | 0.50 |
sCD40L (pg/mL) | 88.8 ± 81.8 | 53.3 ± 43.6 | 0.89 |
IL-17A (pg/mL) | 9.1 ± 12.2 | 7.6 ± 15.5 | 0.31 |
IL-6 (pg/mL) | 459 ± 2673 | 162 ± 164 | 0.94 |
IL-7 (pg/mL) | 2.9 ± 3.7 | 1.4 ± 1.7 | 0.65 |
IFN-γ (pg/mL) | 0.14 ± 0.91 | 0 | 0.99 |
Platelet-Fg (%) | 28.1 ± 27.8 | 56.5 ± 31.2 | 0.0054 |
Platelet-Fg (MFI) | 1770 ± 1266 | 2752 ± 1359 | 0.0026 |
Platelet-PS (%) | 2.9 ± 2.4 | 3.5 ± 2.7 | 0.61 |
Platelet-PS (MFI) | 29.8 ± 15.1 | 37 ± 18.3 | 0.068 |
Platelets-neutrophils (%) | 3.4 ± 5 | 4.4 ± 6.2 | 0.72 |
Platelets-neutrophils (CD61 MFI) | 313 ± 127 | 323 ± 137 | 0.72 |
Platelets-monocytes (%) | 19.8 ± 23.1 | 22.1 ± 25.5 | 0.73 |
Platelets-monocytes (CD61 MFI) | 1413 ± 2462 | 1569 ± 3182 | 0.82 |