Table 1 Demographics and study design of studies
From: Heart rate variability in critical care medicine: a systematic review
Reference number. author | Year | Study design | Study populations (± comparator group) | Patients (n) | Age (mean ± SD or mean [range]) | Male (%) |
|---|---|---|---|---|---|---|
20. Annane | 1999 | Case–control | Sepsis (healthy controls) | 26 | Septic shock 52 ± 14 Sepsis 54 ± 17 Control 43 ± 11 | 65 |
21. Korach | 2001 | Cohort | Sepsis | 41 | 50 [20–90] | 44 |
22. Barnaby | 2002 | Cohort | Sepsis | 15 | 59 [39–85] | – |
23. Pontet | 2003 | Case–control | Sepsis + MODS (Sepsis − MODS) | 22 | MODS 59.5 ± 17.8 Non-MODS 60 ± 10.4 | 64 |
24.Shen | 2003 | Cohort | Weaning | 24 | Successful wean 76 ± 12.9 Unsuccessful wean 69.8 ± 17.8 | 42 |
25. Schmidt | 2005 | Cohort | MODS (literature values) | 85 | 60.4 ± 14 | 62 |
26. Papaioannou | 2006 | Cohort | MODS | 53 | 63.02 ± 14.68 | 58 |
44. Bourgault | 2006 | Cohort | Mixed aetiology | 18 | 60 [33–82] | 72 |
45. Chen | 2007 | Cohort | Sepsis | 81 | 67 [30–84] | 41 |
50. Passariello | 2007 | Case–control | Ischaemic sudden death | 40 | Sudden death 66 ± 8 Pathology matched controls 68 ± 8 |  |
46. Chen | 2008 | Cohort | Sepsis | 132 | 67 [27–86] | 47 |
47. Aboab | 2008 | Case–control | Sepsis ± adrenal insufficiency (healthy controls) | 81 | Septic shock and adrenal failure 55 ± 16 Septic shock 58 ± 19 Healthy controls (not provided) | 36 |
27. Nogueira | 2008 | Cohort | Sepsis | 31 | Survivors 44.9 ± 5.9 Non-survivors 55.6 ± 4.63 | 74 |
28. Papaioannou | 2009 | Cohort | Sepsis (Sepsis SOFA <10) | 45 | 57.8 | – |
51. Tiainen | 2009 | Cohort | Out of hospital cardiac arrest | 70 | Hypothermia 60 (23–75) Normothermia 59 (18–75) | 86 |
29. Schmidt | 2010 | Case–controla | MODS | 178 | 61.1 ± 13.2 | 67 |
30. Kasaoka | 2010 | Cohort | SIRS | 10 | 53 ± 15 | 70 |
31. Chen | 2012 | Case–control | Sepsis and out of hospital cardiac arrest (Non-severe sepsis and healthy controls) | 210 | Out of hospital cardiac arrest 68 ± 10 Severe sepsis and mechanical ventilation 66 ± 8 Severe sepsis 68 ± 7 Sepsis 67 ± 6 Healthy 66 ± 6 | 55 |
32.Gomez Duque | 2012 | Cohort | Sepsis (literature values) | 100 | 55 [18–88] | 42 |
33. Brown | 2013 | Cohort | Sepsis | 48 | 57 [40–63] | 46 |
34. Green | 2013 | Cohort | MODS | 33 | 56.5 ± 15.9 | 61 |
35.Wieske | 2013 | Cohort | ICU acquired weakness | 83 | ICU acquired weakness 60 ± 13 No ICU acquired weakness 59 ± 16 | 60 |
36. Wieske | 2013 | Cohort | Mixed aetiology (healthy controls) | 32 | Patients 54 ± 15 Healthy control 36 ± 2 | 70 |
37. Bradley | 2013 | Cohort | Mixed aetiology | 33 | 56.5 ± 15.9 | 61 |
38. Huang | 2014 | Cohort | Mixed aetiology | 101 | Successful 65 ± 18 Unsuccessful 71 ± 16 | 65 |
39. Zhang | 2014 | Cohort | SIRS/MODS (non-MODS) | 41 | 47 [34–59] | 54 |
40. Schmidt | 2014 | Case–controla | CCF and MODS (literature values) | 130 | CCF 63 ± 10.1 MODS 62.8 ± 10.2 | 63 |
52. Tang | 2014 | Case–control | Stroke | 227 | AF stroke 74 ± 12 Non-AF stroke 62 ± 15 Age/sex-matched controls 61 ± 10 | 40 |
41. Zaal | 2015 | Case–control | ICU delirium (no delirium) | 25 | ICU delirium 67 ± 12 No ICU delirium 57 ± 16 | 72 |
42. Hammash | 2015 | Cohort | Weaning | 35 | 53.3 ± 14.6 | 66 |
53. Nagaraj | 2016 | Case seriesa | Not specified | 40 | 56.3 ± 16.8 | 62.5 |