Table 4 Physiologic variables and hypoperfusion
Variable | Group | 0 h | 3 h | 6 h | p |
|---|---|---|---|---|---|
P peak | Protective (n = 8) | 19 ± 2 | 21 ± 3 | 22 ± 3 | |
(cmH2O) | Control (n = 8) | 18 ± 2 | 20 ± 2 | 21 ± 2 | 0.35 |
P mean | Protective (n = 8) | 13 ± 1 | 13 ± 1 | 13 ± 2 | |
(cmH2O) | Control (n = 8) | 9 ± 1 | 9 ± 1 | 9 ± 1 | <0.01* |
P plateau | Protective (n = 8) | 18 ± 2 | 19 ± 2 | 20 ± 3 | |
(cmH2O) | Control (n = 8) | 17 ± 2 | 20 ± 2 | 21 ± 2 | <0.05* |
CI | Protective (n = 8) | 2.6 ± 0.6 | 2.0 ± 0.2 | 2.1 ± 0.5 | |
(L x min−1 x m−2) | Control (n = 8) | 3.2 ± 0.7 | 2.5 ± 0.3 | 2.4 ± 0.8 | <0.05* |
MAP | Protective (n = 8) | 80 ± 16 | 68 ± 9 | 69 ± 14 | |
(mmHg) | Control (n = 8) | 93 ± 22 | 79 ± 15 | 75 ± 20 | <0.05* |
MPAP | Protective (n = 8) | 21 ± 2 | 23 ± 3 | 27 ± 5 | |
(mmHg) | Control (n = 8) | 22 ± 4 | 29 ± 14 | 34 ± 14 | <0.05* |
HR | Protective (n = 8) | 105 ± 19 | 84 ± 15 | 88 ± 16 | |
(beats x min−1) | Control (n = 8) | 103 ± 20 | 94 ± 9 | 111 ± 12 | 0.06 |
PCWP | Protective (n = 8) | 10 ± 3 | 9 ± 1 | 9 ± 2 | |
(mmHg) | Control (n = 8) | 9 ± 3 | 9 ± 4 | 9 ± 4 | 0.93 |
Temperature | Protective (n = 8) | 38.3 ± 0.6 | 37.8 ± 0.5 | 37.8 ± 0.8 | |
(°C) | Control (n = 8) | 38.4 ± 0.9 | 38.6 ± 0.9 | 39.1 ± 1.0 | <0.01* |
Lactate | Protective (n = 8) | 1.6 ± 0.5 | 1.3 ± 0.3 | 1.1 ± 0.2 | |
(mmol x L−1) | Control (n = 8) | 1.8 ± 0.4 | 1.6 ± 0.7 | 1.5 ± 0.6 | 0.18 |