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Fig. 5 | Intensive Care Medicine Experimental

Fig. 5

From: Cardiopulmonary bypass in the newborn: effects of circulatory cell-free hemoglobin and hyperoxia evaluated in a novel rat pup model

Fig. 5

Hb- and heme-scavenging systems following exposure to cell-free human Hb and/or hyperoxia. Plasma concentrations (a, c) and mRNA expression in liver (b, d) of Hp (a, b) and Hpx (c, d) at 3–24 h following i.p. injection. Fold change mRNA expression was calculated against VN-mean at each time point. n = 5–18 in all groups. Results are presented as mean ± SD for a and c and as box-and-whisker plots with min and max values marked for b and d

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