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Table 1 Gas exchange and respiratory mechanics

From: Effects of regional perfusion block in healthy and injured lungs

 

Group

 
 

1

2

3

4

5

p value (ANOVA)

PaO2/FiO2

52 ± 14

598 ± 20

530 ± 84

533 ± 44

271 ± 128

0.001

PaO2

(mmHg)

156 ± 4

598 ± 20

530 ± 84

533 ± 44

271 ± 128

< 0.001

PaCO2

(mmHg)

44 ± 3

47 ± 2

32 ± 3

38 ± 5

49 ± 4

< 0.001

V T

(ml)

526 ± 14

532 ± 18

1447 ± 120

1190 ± 122

1147 ± 161

< 0.001

RR

(breaths per minute)

20 ± 1

19 ± 1

9 ± 0

10 ± 2

10 ± 2

< 0.001

P plat

(cmH2O)

19.0 ± 0.6

19.5 ± 2.3

37.7 ± 2.9

35.0 ± 5.4

40.9 ± 2.7

< 0.001

P peak

(cmH2O)

22.0 ± 0.8

22.4 ± 2.6

43.9 ± 3.2

43.1 ± 2.4

45.6 ± 1.6

< 0.001

E RS

(cmH2O L−1)

27.6 ± 0.6

28.3 ± 3.7

27.9 ± 3.9

30.9 ± 3.1

37.1 ± 5.9

0.057

E L

(cmH2O L−1)

18.9 ± 1.3

18.8 ± 1.2

23.3 ± 6.1

23.5 ± 7.8

26.7 ± 9.4

0.35

  1. Data are reported as mean ± standard deviation
  2. Group 1 control; group 2 the right lower lobe perfusion block with protective ventilation; group 3 lung lavage, high V T ventilation; group 4 as group 3 plus the right lower lobe perfusion block; group 5 as group 3 plus the left lower lobe perfusion block; PaO 2 /FiO 2 ratio of partial arterial oxygen pressure to inspired oxygen fraction; PaO 2 arterial oxygen partial pressure; V T tidal volume; RR respiratory rate; P plat plateau pressure; P peak peak airway pressure; E RS elastance of the respiratory system; E L lung elastance
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