Effects of regional perfusion block in healthy and injured lungs

Intensive Care Medicine Experimental

Table 2 Hemodynamics

Group	1	2	3	4	5	p value
Mean AP (mmHg)	86 ± 7	91 ± 15	85 ± 7	85 ± 17	87 ± 11	0.98
Mean PAP (mmHg)	18.9 ± 1.7	22.1 ± 5.6	24.9 ± 2.8	27.5 ± 4.8	34.7 ± 2.8	0.004
Wedge (cmH₂O)	11.8 ± 0.2	12.2 ± 1.1	12.2 ± 0.9	11.6 ± 1.0	12.7 ± 1.0	0.643
HR (bpm)	79 ± 18	66 ± 4	70 ± 14	81 ± 13	90 ± 2	0.214
CO (L min⁻¹)	7.26 ± 1.87	5.63 ± 1.87	4.82 ± 1.39	4.68 ± 0.63	5.67 ± 0.54	0.128
PVR (mmHg L⁻¹ min⁻¹)	1.10 ± 0.18	2.13 ± 1.49	3.40 ± 1.50	3.96 ± 1.78	4.20 ± 0.75	0.094

Data are reported as mean ± standard deviation
Group 1 control; group 2 the right lower lobe perfusion block with protective ventilation; group 3 lung lavage, high V _T ventilation; group 4 as group 3 plus the right lower lobe perfusion block; group 5, as group 3 plus the left lower lobe perfusion block; AP systemic arterial pressure; PAP pulmonary artery pressure; HR heart rate; CO cardiac output; PVR pulmonary vascular resistance