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Table 2 Baseline and follow-up respiratory and hemodynamic parameters

From: Preliminary experience on the safety and tolerability of mechanical “insufflation-exsufflation” in subjects with artificial airway

  Baseline 5′ 60″ p
Temperature, °C 37.3 ± 0.82   37.4 ± 0.7 ns
Heart rate, bpm 97.7 ± 14.4 97.1 ± 15.1 97.3 ± 14.2 0.82
Mean blood pressure, mmHg 87 ± 11.9 87.6 ± 14.7 83.6 ± 14.7 0.57
Sat O2, % 97.38 ± 2.37 98.3 ± 2.2 97 ± 3.4 0.04
pHa 7.43 ± 0.1 7.38 ± 0.1 7.45 ± 0.05 0.17
pHv 7.39 ± 0.1 7.44 ± 0.02 7.42 ± 0.05 0.13
PaO2, mmHg 105.5 ± 23.9 124 ± 55.5 *143 ± 42.3 0.031
PvO2, mmHg 54.9 ± 37.4 34.5 ± 4.9 52.4 ± 29 0.67
PaCO2, mmHg 37.5 ± 12.6 40.5 ± 13.3 35.2 ± 8.2 0.058
PvCO2, mmHg 45.2 ± 6.7 44.5 ± 3.5 40.2 ± 5.2 0.15
Ventilator mode     0.61
 CPAP PC-IMV 20   18  
 MMV VC-IMV 2   1  
 Spontaneous respiration 4   7  
FiO2 0.46 ± 0.13 0.45 ± 0.13 0.44 ± 0.1 0.73
PaO2/FiO2 239.8 ± 96.8 285.5 ± 140 328.7 ± 104.7 0.14
PvO2/FiO2 134.9 ± 114.2 105.9 ± 3.7 132.6 ± 93.9 0.96
Total breath, rate/min 22.1 ± 6.3 23.5 ± 7.1 20.7 ± 5.9 0.10
Minute volume, l/min 10.6 ± 3.6 11.0 ± 3.2 9.6 ± 2.6 0.13
Tidal volume, ml 524.1 ± 106.6 496.3 ± 118.4 493.2 ± 139 0.15
PEEP, mmHg 5.3 ± 2.9 5.3 ± 2.9 4.6 ± 3.2 0.45
Peak inspiratory pressure, cmH2O 23.6 ± 7.8 24.0 ± 8.1 22.3 ± 5.6 0.17
Plateau pressure, cmH2O 21.9 ± 5.1 22.5 ± 5.4 20.9 ± 4.4 0.14
Lung compliance
 Dynamic 17.7 ± 9.5 16.3 ± 9.4 17.6 ± 9.6 0.4
 Static, ml/cmH2O 18.7 ± 8.8 17.2 ± 9.1 19.1 ± 9.3 0.33
CA tidal volume, ml 1043.6 ± 649.9    
  1. Bpm beats per minute, Sat O 2 pulse-oximetry oxygen saturation, pHa arterial pH, pHv venous pH, PaO 2 arterial oxygen partial pressure, PvO 2 venous oxygen partial pressure, PaCO 2 arterial CO2 partial pressure, PvCO 2 venous CO2 partial pressure, CPAP assisted pressure ventilation, MMV minimal mandatory ventilation, BiPAP controlled pressure mandatory ventilation, IPPV volume-targeted pressure control ventilation, PEEP positive end-expiratory pressure, CA Cough Assist
  2. *Significant difference from baseline