Table 4 Cumulative dose/kg body weight and duration of treatment with sedatives and analgesic agents throughout the study period
From: Allostasis and sedation practices in intensive care evaluation: an observational pilot study
Drugs given | Standard care n = 16 | No. treated | All-SPICE n = 12 | No. treated | P value |
|---|---|---|---|---|---|
Dexmedetomidine (mcg/kg/day) | 0 [0–0] | 1 | 0 [0–0] | 1 | 0.7460 |
Time on dexmedetomidine (day) | 0 [0–0] | 0 [0–0] | > 0.9999 | ||
Propofol (mg/kg/day) | 11.33 [6.77–19.29] | 16 | 9.63 [2.74–30.7] | 11 | 0.8667 |
Time on propofol (day) | 2.5 [2.0–4.5] | 1.0 [0.5–3.0] | 0.0139 * | ||
Midazolam (mg/kg/day) | 0.037 [0–0.18] | 8 | 0.010 [0–1.17] | 10 | 0.466 |
Time on midazolam (day) | 0.5 [0.0–2.0] | 2.0 [1.0–4.0] | 0.0283 * | ||
Fentanyl (mcg/kg/day) | 0 [0–2.67] | 7 | 11.14 [8.08–26.18] | 11 | 0.0002 * |
Morphine (mg/kg/day) | 0.153 [0–0.59] | 10 | 0.20 [0–1.99] | 6 | 0.576 |