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Fig. 2 | Intensive Care Medicine Experimental

Fig. 2

From: A mathematical model of CO2, O2 and N2 exchange during venovenous extracorporeal membrane oxygenation

Fig. 2

Effect on SaO2 of different approaches to managing \( {\dot{V}}_{\mathrm{SWEEP}} \). Results for when PaCO2 is held constant at 40 mmHg by varying \( {\dot{V}}_{\mathrm{SWEEP}} \) (continuous lines) compared to when \( {\dot{V}}_{\mathrm{SWEEP}} \)is held constant at 5 l/min (data points as red markers). As \( {\dot{Q}}_{EC} \) increases, SaO2 rises. The higher the \( \frac{{\dot{Q}}_S}{{\dot{Q}}_T} \), the higher the \( {\dot{Q}}_{EC} \) required to achieve “acceptable” values of SaO2 > 85%. The red dots of fixed \( {\dot{V}}_{\mathrm{SWEEP}} \) = 5 l/min match the curves of variable \( {\dot{V}}_{\mathrm{SWEEP}} \) (fixed PaCO2), demonstrating that the approach taken to managing \( {\dot{V}}_{\mathrm{SWEEP}} \) has minimal effect on SaO2

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