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Fig. 2 | Intensive Care Medicine Experimental

Fig. 2

From: Body temperature and mouse scoring systems as surrogate markers of death in cecal ligation and puncture sepsis

Fig. 2

Modified Mouse Grimace Scale (MGS) score over time (a), MGS score as a predictor of death in septic mice (b), and MGS individual component scores (cf) over time in mice undergoing moderate or severe CLP. Data are presented as mean ± SEM from six independent experiments representing a total number of n = 18 sham, n = 23 moderate CLP, and n = 17 severe CLP mice; *p < 0.05, **p < 0.01 (vs. line of identity in (b)), ***p < 0.001 vs. sham; ###p < 0.001 vs. moderate CLP, by two-way ANOVA. Note: Only two mice undergoing severe CLP survived past 18 h, therefore statistical comparisons were not performed at this time-point (a, cf). Dotted line in (b) represents the line of identity for statistical comparison in ROC analyses. AUC area under the curve, 95% CI 95% confidence interval

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