Skip to main content

Table 1 Effect of antibiotic on gain and loss of resistance in Enterobacteriaceae after 72 h in ICU

From: Ecological effects of cefepime use during antibiotic cycling on the Gram-negative enteric flora of ICU patients

Resistance

Treatmenta

Gainedb

Lostb

No changec

Sensitive

Resistant

Timentin and/or gentamicin

Cefepime

15

7

22

17

APP-β

14

6

45c

13

None

13

3

43a

8

 

p = 0.610

p = 0.34

p = 0.004a

p = 0.07

Timentin

Cefepime

15

8

22

16

APP-β

14

6

45a

13

None

12

3

44a

8

 

p = 0.550

p = 0.20

p = 0.002a

p = 0.10

Gentamicin

Cefepime

8

7

39

7

APP-β

6

8

62a

2

None

5

2

57a

3

 

p = 0.456

p = 0.16

p = 0.014a

p = 0.06

  1. aAPP-β, antipseudomonal penicillin/β-lactamase; none, no cefepime or APP-β
  2. bNumber of patients
  3. cSignificant difference (p < 0.05)