Fig. 1

Effect of P8RI on mesenteric ischemia/reperfusion-induced intestinal injury. Ischemia/reperfusion-induced intestinal injury was assessed by histological analysis using Chiu’s score that ranges from a normal mucosa (score = 0) to a total mucosal necrosis (score = 6), and morphometric analysis using Qwin software from scanned histological sections by a nanozoomer in I/R controls, P8RI, and sham groups. a The Chiu’s score of intestinal injury was lower in the P8RI group compared to I/R controls (*P = 0.01). b The epithelial area was higher in the P8RI group than in I/R controls (**P = 0.001). c The intestinal luminal hemoglobin concentration only tended to be lower in the P8RI group than in I/R controls, without reaching statistical significance (P = 0.09)