Fig. 2

Effect of P8RI on mesenteric ischemia/reperfusion-induced neutrophil activation. Mesenteric ischemia/reperfusion-induced neutrophil activation was assessed by the detection of MMP-9 and MPO release in the small bowel tissue and plasma. a, b The concentrations of MMP-9 and MPO in the intestinal tissue were almost significantly lower in the P8RI group than in I/R controls (P = 0.06 and P = 0.058, respectively). c The plasma concentration of MMP-9 was lower in the P8RI group than in I/R controls at 3 h (**P < 0.001) and 4 h (**P < 0.001) of reperfusion after mesenteric ischemia. MMP-9: matrix metalloproteinase-9