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Fig. 3 | Intensive Care Medicine Experimental

Fig. 3

From: Clinical-grade mesenchymal stem cells derived from umbilical cord improve septic shock in pigs

Fig. 3

UCMSCs attenuate sepsis-induced organ failure. Lung function was monitored by assessing the PaO2/FIO2 ratio (a) and based on histology (d). Renal function was assessed by measuring plasma creatinine concentration (b), fluid balance (c), and by histological observation (e). For histological scoring, a score of 0 corresponds to an absence of anomaly, 1 reflects discrete anomalies, 2 corresponds to moderate anomalies, and 3 indicates severe anomalies. Histological images (hematoxylin-eosin staining, × 40 magnification) are representative of the respective conditions. *p < 0.05; **p < 0.01;***p < 0.001; ****p < 0.0001 versus control group

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