Fig. 1
From: Advanced modes of mechanical ventilation and optimal targeting schemes

Relation between cost functions and targets. Every cost function (tidal volume, tidal pressure, tidal power, breathing power, inspiratory power, and inspiratory pressure) was minimized analytically or using mathematical simulation. The result is the “optimal” ventilation frequency, which reaches the set alveolar minute ventilation and minimizes the cost function. After that, the frequency was used to calculate the target tidal volume