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Fig. 1 (abstract P49). | Intensive Care Medicine Experimental

Fig. 1 (abstract P49).

From: Sepsis 2018

Fig. 1 (abstract P49).

Seahorse assay parameters in healthy controls, low and high risk infection groups, measured in oxygen consumption rate (OCR). OCR represents cellular metabolism through mitochondrial respiration. Basal denotes baseline energetic demand of the cell; maximal respiration shows the maximum rate of respiration the cell can achieve; spare respiratory capacity denotes the capability of the cell to respond to energetic demand; ATP production shows ATP produced by the mitochondria to meet the cellular energetic need. p value (2-way ANOVA): ns >0.05, *0.01-0.05, ****<0.0001. Notably, this reduced mitochondrial respiration was not accompanied by a compensatory increase in glycolysis (Fig. 2)

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