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Table 1 Systemic hemodynamic, gas exchange, and acid-base status

From: Intravenous hydrogen sulfide does not induce neuroprotection after aortic balloon occlusion-induced spinal cord ischemia/reperfusion injury in a human-like porcine model of ubiquitous arteriosclerosis

Parameter

Group

NaCl

Na2S

Core temp. (°C)

Baseline

32 (31.8–32.1)

31.8 (31.5–32.0)

4 h reperfusion

32 (31.8–32.0)

32.0 (31.9–32.1)

8 h reperfusion

32 (31.8–32.1)

32.0 (32.0–32.0)

Hemoglobin (g L−1)

Baseline

83 (71–88)

82 (74–94)

4 h reperfusion

101 (92–108)

101 (81–123)

8 h reperfusion

98 (83–107)

102 (82–132)

Heart rate (bpm)

Baseline

72 (62–81)

74 (54–94)

4 h reperfusion

89 (47–109)

112 (89–135)

8 h reperfusion

82 (49–109)

106 (78–130)

CVP (mmHg)

Baseline

8 (5–10)

7 (4–10)

4 h reperfusion

9 (7–10)

7 (5–9)

8 h reperfusion

8 (7–10)

7 (4–9)

CI (ml kg−1 min−1)

Baseline

84.4 (64.2–102.8)

72.5 (61.9–78.3)

4 h reperfusion

85.1 (48.6–125)

90.7 (70.3–121)

8 h reperfusion

80.0 (48.8–108.3)

83.7 (54.5–120)

MAP (mmHg)

Baseline

82 (63–93)

77 (70–86)

4 h reperfusion

82 (78–91)

84 (59–107)

8 h reperfusion

84 (78–88)

81 (69–95)

ITBVI (mL m−2)

Baseline

636 (537–786)

629 (482–762)

4 h reperfusion

727 (509–1173)

612 (496–805)

8 h reperfusion

665 (587–780)

577 (509–742)

Arterial pO2 (mmHg)

Baseline

168 (147–189)

151 (134–161)

4 h reperfusion

169 (136–187)

126 (92–150)

8 h reperfusion

171 (145–187)

120 (91–138)

Arterial pCO2 (mmHg)

Baseline

39 (37–39)

38 (35–43)

4 h reperfusion

36 (33–38)

42 (35–47)

8 h reperfusion

39 (36–41)

42 (39–48)

Horowitz index (mmHg)

Baseline

584 (490–630)

604 (536–640)

4 h reperfusion

562 (543–623)

505 (368–600)

8 h reperfusion

569 (483–623)

483 (364–552)

Arterial pH

Baseline

7.48 (7.42–7.56)

7.52 (7.46–7.56)

4 h reperfusion

7.43 (7.36–7.50)

7.37 (7.29–7.49)

8 h reperfusion

7.41 (7.34–7.50)

7.32 (7.10–7.44)

Arterial base excess (mmol L−1)

Baseline

5.2 (0.8–10.8)

7.9 (3,2–11.5)

4 h reperfusion

0,1 (− 4.6–3.6)

1.2 (− 4–3.2)

8 h reperfusion

0.1 (− 3.8–4.5)

− 4,3 (− 15.3–2.4)

Na+ (mmol L−1)

Baseline

138 (133–141)

138 (137–139)

4 h reperfusion

141 (139–143)

142 (139–142)

8 h reperfusion

142 (141–143)

139 (129–144)

K+ (mmol L−1)

Baseline

3.4 (3.1–3.7)

3.8 (3.6–4.2)

4 h reperfusion

3.9 (3.8–4.1)

4.1 (3.8–4.7)

8 h reperfusion

3.9 (3.9–4.0)

3.9 (3.4–4.5)

Glucose (mg dL−1)

Baseline

114 (105–136)

144 (103–172)

4 h reperfusion

169 (155–202)

185 (126–239)

8 h reperfusion

159 (88–222)

160 (124–235)

  1. All data are median (range); sodium chloride (vehicle, NaCl) n = 4 and sodium sulfide (Na2S) n = 4. h hours, CVP central venous pressure, CI cardiac index, ITBV intra-thoracic blood volume index, MAP mean arterial pressure