Table 1 Final study (4 and 5 of 5 studies) interventions distributed along different time points

Central lines, intubation, and ventilation set up.

Infusions and intracardiac catheterization.

Arterial catheter and withdrawal pump set up.

Spleen ligation.

T0

Baseline injection of color-coded microspheres

Burr-holes completion

Head injury model

PTi02 and ICP proves insertion

T1

First injection of color-coded microspheres

Anemia model

T2

Second injection of color-coded microspheres

T3

Third injection of color-coded microspheres

Self-transfusion model

T4

Fourth injection of color-coded microspheres

Euthanasia and organ retrieval