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Table 2 Physiological parameters measured

From: Fluid sparing and norepinephrine use in a rat model of resuscitated haemorrhagic shock: end-organ impact

 

Sham

N = 10

HS: FR + NE

N = 10

HS: FR

N = 10

P

FR vs F+NE

Lactates, mmol/l

 Baseline

0.56 ± 0.11

0.66 ± 0.12

0.47 ± 0.07

NS

 Reperfusion#

0.77 ± 0.20

1.50 ± 0.22

1.16 ± 0.27

NS

 Delta lactate

0.21 ± 0.18

0.76 ± 0.34§

0.69 ± 0.29§

NS

pH

 Baseline

7.38 ± 0.03

7.42 ±0.03

7.48 ±0.04

NS

 Reperfusion#

7.37 ± 0.01

7.37 ±0.03

7.41 ±0.03

NS

PaO2, mmHg

 Baseline

328 ± 31

336 ± 30

309 ± 49

NS

 Reperfusion#

334 ± 28

339 ± 24

301 ± 18

NS

Creatinine, mg/dl

 Baseline

0.32 ± 0.05

0.33 ±0.03

0.29 ± 0.05

NS

 Reperfusion#

0.34 ± 0.07

0.71 ±0.11§

0.53 ± 0.10

NS

 Euthanasia

0.26 ± 0.08

0.32 ±0.06

0.26 ± 0.03

NS

Delta creatinine A*, mg/dl

0 ± 0.04

0.30 ±0.08§

0.20 ± 0.05

NS

Delta creatinine B**, mg/dl

0 ± 0.06

± 0.06

0 ± 0.06

NS

  1. Values are reported as Mean ± SEM. #Measured at the end of the reperfusion period
  2. *Delta creatinine A (end of reperfusion-baseline); ** Delta creatinine B (at euthanasia-baseline). §p < 0.05 vs sham