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Table 1 Body weight, oxygenation, blood pressure, and compliance during the mechanical ventilation

From: Angiotensin-(1–7) exerts a protective action in a rat model of ventilator-induced diaphragmatic dysfunction

  Body weight (g) PaO2 (mmHg) Mean blood pressure (mmHg) Respiratory system static compliance (ml/cmH2O)
Start End Start End
CTRL 282 ± 34 0.44 ± 0.04
Vehicle 279 ± 32 94 ± 15 101 ± 22 91 ± 35 0.41 ± 0.03 0.33 ± 0.05
Ang-(1–7) 275 ± 37 100 ± 6 96 ± 18 91 ± 36 0.41 ± 0.08 0.32 ± 0.05
Ang-(1–7) + A-779 277 ± 30 91 ± 9 99 ± 16 95 ± 43 0.40 ± 0.06 0.32 ± 0.03
Ang-(1–7) + A-779 + PD 276 ± 16 102 ± 11 103 ± 25 139 ± 17* 0.42 ± 0.05 0.34 ± 0.05
ANOVA NS NS NS 0.022 NS NS
  1. CTRL (n = 10): unventilated controls; vehicle (n = 18): VIDD + saline treatment; Ang-(1–7) (n = 14): VIDD + Ang-(1–7) treatment; Ang-(1–7) + A-779 (n = 10): VIDD + Ang-(1–7) + A-779 treatment; Ang-(1–7) + A-779 + PD (n = 8): VIDD + Ang-(1–7) + A-779 + PD123319 treatment; *p = 0.018 vs Ang-(1–7), p = 0.044 vs Ang-(1–7) + A-779