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Table 1 Clinical score (all changes refer to the baseline)

From: Time-related changes in hepatic and colonic mitochondrial oxygen consumption after abdominal infection in rats

Examination

Results

 

Body weight

Weight loss in %

% < 5 ⇒ 0 P

% 5–15 ⇒ 2 P

% 15–20 ⇒ 3 P

% > 20 ⇒ 10 P

Appearance

1. Normal appearance, fur smooth, clean

⇒ 0 P

2. Slight grooming deficiency, rough fur

⇒ 1 P

3. Increasing grooming deficiency, rings around eyes, anus

⇒ 2 P

4. Clear grooming deficiency, crusty eyes, bedding sticks to anus

⇒ 3 P

Spontaneous behaviour

1. Rat investigates cage, active

⇒ 0 P

2. Rat remains in one place, movement of entire body present

⇒ 1 P

3. Hunched posture, swaying gait

⇒ 3 P

4. Immobile, lateral position

⇒ 10 P

Provoked behaviour

1. Rat flees when opening cage, strong muscle tonus

⇒ 0 P

2. Rat flees when hand approaches

⇒ 1 P

3. Rat flees when touched

⇒ 2 P

4. No flight reaction

⇒ 3 P

Breathing frequency

Difference in %

% < 10 ⇒ 0 P

% 10–20 ⇒ 1 P

% 20–50 ⇒ 2 P

% > 50 ⇒ 3 P

Expiratory breathing sound

No

⇒ 0 P

Yes

⇒ 1 P

Abdominal palpation

1. No pain when applying pressure, soft abdomen

⇒ 0 P

2. Slight reaction to abdominal palpation, soft abdomen

⇒ 1 P

3. Clear pain reaction to abdominal palpation, abdominal resistance

⇒ 2 P

4. Clear pain reaction to abdominal palpation, hard abdomen

⇒ 3 P

Condition of droppings

1. A lot of normal droppings in cage, defecating during examination

⇒ 0 P

2. A lot of droppings in cage, droppings with blood, runny or mucous

⇒ 1 P

3. Few droppings in cage, independent of the condition

⇒ 2 P

4. No droppings in cage

⇒ 3 P