Time-related changes in hepatic and colonic mitochondrial oxygen consumption after abdominal infection in rats

Intensive Care Medicine Experimental

Table 2 Laboratory chemical parameters for organ damage: creatinine and urea for kidney; AST, ALT, and LDH for liver

	Creatinine (mg/dl)	Urea (mg/dl)	AST (U/l)	ALT (U/l)	LDH (U/l)
Control	0.32 ± 0.15	32.33 ± 5.79	67.17 ± 14.32	47.67 ± 8.87	236.83 ± 143.83
Sham 24 h	0.28 ± 0.06	39.25 ± 9.20	148.25 ± 61.92*	53.92 ± 16.53	216.50 ± 82.32
CASP 24 h	0.29 ± 0.03	33.60 ± 4.33	138.30 ± 37.48*	41.00 ± 12.21^#	182.70 ± 24.47
Sham 48 h	0.28 ± 0.05	36.33 ± 6.34	103.33 ± 41.41	52.33 ± 7.01	211.33 ± 194.04
CASP 48 h	0.35 ± 0.18	52.16 ± 36.37^{* #}	124.83 ± 52.93*	49.17 ± 16.61	237.17 ± 150.08
Sham 72 h	0.29 ± 0.03	34.75 ± 4.33	75.33 ± 11.02	49.00 ± 9.67	151.92 ± 44.8
CASP 72 h	0.31 ± 0.03	39.92 ± 4.40	65.00 ± 9.87	40.17 ± 7.92	137.67 ± 30.12
Sham 96 h	0.33 ± 0.05	37.25 ± 3.22	87.83 ± 36.12	53.67 ± 16.79	163.58 ± 75.78
CASP 96 h	0.30 ± 0.00	33.67 ± 6.20	87.83 ± 42.65	42.75 ± 9.96	180.58 ± 156.22

Data are shown as mean ± SD, *p < 0.05 vs. controls, #p < 0.05 vs. sham (controls n = 9, sham n = 12, CASP 24 h n = 11, other CASP groups n = 12)