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Fig. 1 | Intensive Care Medicine Experimental

Fig. 1

From: Bradykinin receptor deficiency or antagonism do not impact the host response during gram-negative pneumonia-derived sepsis

Fig. 1

Deficiency of BK receptors does not influence K. pneumoniae outgrowth or dissemination during pneumonia-derived sepsis. Bacterial burdens [colony-forming units (CFUs)] in the lung (at 12 h and 36 h), blood, spleen, and liver at 36 h after infection in wild-type (WT) mice and mice with genetic deficiency of B1RB2R (Bdkrb1/b2−/−). Cultures of blood, spleen, and liver were negative at 12 h post infection. Data are depicted as box-and-whisker diagrams (10-Log) of eight mice per group at each time point. Differences between groups were not significant (Mann-Whitney U test)

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