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Fig. 3 | Intensive Care Medicine Experimental

Fig. 3

From: Bradykinin receptor deficiency or antagonism do not impact the host response during gram-negative pneumonia-derived sepsis

Fig. 3

Lung myeloperoxidase (MPO) levels and Ly6-G positive cells in lung tissue during pneumonia in mice with or without B1RB2R deficiency. a MPO was measured in whole lung homogenates (12 and 36 h after infection) from wild-type (WT) mice and mice with genetic deficiency of B1RB2R (Bdkrb1/b2−/−). b Ly6-G positivity of lung tissue was determined by image analysis (12 h after infection). Bar graphs are depicted as box-and-whisker diagrams of eight mice per group at each time point. Lower panel (c) shows representative pictures of Ly6G staining of lung tissue (12 h after infection; original magnification × 4). *P < 0.05 versus WT

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