Table 1 Plasma concentrations of cytokines and endothelial cell activation markers in wild-type and Bdkrb1/b2−/− mice
(pg/ml) | T = 12 h | T = 36 h | ||
|---|---|---|---|---|
Wild-type | Bdkrb1/b2−/− | Wild-type | Bdkrb1/b2−/− | |
IFN-γ | ND | ND | 64 (22–128) | 16 (3–77) |
IL-6 | 17 (7–28) | 30 (22–42) | 252 (118–371) | 137 (37–419) |
IL-10 | ND | ND | 3 (2–7) | 2 (1–10) |
TNF-α | ND | ND | 46 (36–235) | 34 (11–53) |
Soluble E-selectin (ng/ml) | 40 (34–50) | 37 (15–59) | 284 (142–351) | 129 (116–145) |
Soluble VCAM-1 (ng/ml) | 1382 (936–1679) | 1283 (484–1477) | 3526 (2996–4007) | 3158 (1619–3582) |