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Table 1 Plasma concentrations of cytokines and endothelial cell activation markers in wild-type and Bdkrb1/b2−/− mice

From: Bradykinin receptor deficiency or antagonism do not impact the host response during gram-negative pneumonia-derived sepsis

(pg/ml) T = 12 h T = 36 h
Wild-type Bdkrb1/b2−/− Wild-type Bdkrb1/b2−/−
IFN-γ ND ND 64 (22–128) 16 (3–77)
IL-6 17 (7–28) 30 (22–42) 252 (118–371) 137 (37–419)
IL-10 ND ND 3 (2–7) 2 (1–10)
TNF-α ND ND 46 (36–235) 34 (11–53)
Soluble E-selectin (ng/ml) 40 (34–50) 37 (15–59) 284 (142–351) 129 (116–145)
Soluble VCAM-1 (ng/ml) 1382 (936–1679) 1283 (484–1477) 3526 (2996–4007) 3158 (1619–3582)
  1. Data are median with interquartile ranges of eight mice per group at each time point. ND not detectable