Histopathological changes of organ dysfunction in sepsis

Intensive Care Medicine Experimental

Table 1 Summary of findings from kidney tissue samples

	N	Acute tubular necrosis	Glomerulonephritis	Tubulointersticial nephropahty	Pyelonephritis	Vascular injury	Apoptosis
Mustonen et al. [17]	57	4 (7.0%)	4 (7.0%)	47 (82.0%)	2 (3.5%)
Hotchkiss et al. [18]	12	1 (0.83%)
Diaz de leon et al. [19]	40	20 (50.0%)	11 (27.5%)*			9 (22.5%)
Sato et al. [20]	6	1 (17.0%)
Langerberg et al. [23]	117	26 (22.0%)
Lerolle et al. [24]	19		19 (100.0%)	19 (100.0%)		4 (21.0%)	19 (100.0%)
Takasu et al. [25]	20			15.6 (78.0%)
Kosaka et al. [26]	1059	184 (17.4%)		915 (86.4%)			953 (90.0%)

Single-case studies are not included in this table. Only studies involving human subjects are considered.^*Reported in the original study as a combined finding of glomerulonephritis or tubulointersticial nephropathy