Table 3 Randomized controlled studies in lung-protective ventilation and PaCO2 levels
Study | Mortality benefit | PaCO2 in control arm (mmHg ± SD) | PaCO2 in LPV arm (mmHg ± SD) | Buffer used |
|---|---|---|---|---|
ARDSNet [2] | Yes | 35.8 ± 8.0 | 40.0 ± 10.0 | Yes |
Amato et al. [66] | Yes | 36.0 ± 1.5 | 58.0 ± 3.0 | No |
Brochard et al. [46] | No | 41.0 ± 7.5 | 59.5 ± 19.0 | No |
Brower et al. [67] | No | 40.1 ± 1.6 | 50.3 ± 3.5 | Yes |
Stewart et al. [68] | No | 46.1 ± 10 | 54.5 ± 15 | No |