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Intensive Care Medicine Experimental

Table 1 Vital parameters at baseline and after induction of injury

From: Use of a high platelet-to-RBC ratio of 2:1 is more effective in correcting trauma-induced coagulopathy than a ratio of 1:1 in a rat multiple trauma transfusion model

Parameter

Standard PLT dose

High PLT dose

Before injury

After injury

Before injury

After injury

Weight (gram)

372 (364–384)

ND

388 (366–395)

ND

MAP (mmHg)

132 (124–144)

42 (32–53)

136 (121–149)

57 (43–67)

HR (bpm)

280 (260–300)

280 (208–308)

280 (273–288)

240 (220–260)

Temperature (°C)

36.6 (36.0–37.4)

37.0 (36.6–37.2)

36.3 (36.0–36.4)

36.8 (36.3–37.0)

pH

7.46 (7.35–7.50)

7.36 (7.22–7.39)

7.39 (7.36–7.42)

7.37 (7.31–7.40)

pCO2 (mmHg)

36.1 (30.7–39.4)

28.1 (19.1–36.5)

42.0 (39.5–43.4)

34.3 (31.4–36.8)

BE (mmol/L)

0.7 (−2.9–1.3)

− 6.4 (− 18.2 to − 4.3)

− 0.3 (− 1.7 to − 0.6)

− 5.1 (− 9.5 to − 3.8)

Lactate (mmol/L)

1.0 (0.6–1.2)

3.1 (1.9–9.8)

0.8 (0.6–1.0)

3.4 (2.6–4.5)

Hb (mmol/L)

8.5 (8.2–9.2)

6.8 (6.5–7.4)

9.7 (9.1–10.4)

7.6 (7.0–7.9)

  1. Data are presented as median (IQR)
  2. PLT platelet transfusion, MAP mean arterial pressure, HR heart rate, bpm beats per minute, BE base excess, Hb hemoglobin, ND not determined
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