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Intensive Care Medicine Experimental
Fig. 1 | Intensive Care Medicine Experimental

Fig. 1

From: Time-controlled adaptive ventilation (TCAV) accelerates simulated mucus clearance via increased expiratory flow rate

Fig. 1

a Excised, preserved porcine lungs (Nasco BioQuest® Inflatable Lungs Kit, product number LS03765U). b Simulated mucus (3 mL) installed into the middle of the ETT. The proximal edge of the mucus aliquot was marked on the outside of the ETT with a marking pen prior to initiation of mechanical ventilation for each trial run. c At the end of each run, the proximal edge of the mucus aliquot was measured again. From these two measurements, the proximal mucus movement was calculated. d Ventilator waveforms and settings according to the standard TCAV protocol [8]. The top left graph shows the typical APRV pressure waveform, with a long inspiratory duration followed by a quick expiratory release. The bottom left graph shows the rapid flows generated by the specific TCAV breath

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