Table 1 (abstract P13). Baseline characteristics of enrolled patients and comparison between preperiod and postperiod
From: Sepsis 2019
| Â | Pre (N = 317) | Post (N = 231) | P value |
|---|---|---|---|
Age (years), median (IQR) | 71 (60-79) | 73 (62-82) | 0.148 |
Male, no. (%) | 158 (49.8) | 115 (49.8) | 0.996 |
Initial q-SOFA ≥2, no. (%) | 317 (100) | 231 (100) |  |
Site of infection, no (%) | |||
 Respiratory | 198 (62.5) | 135 (58.4) | 0.315 |
 Genitourinary | 83 (26.2) | 61 (26.4) | 0.572 |
 Gastrointestinal | 22 (6.9) | 17 (7.4) |  |
 Hepatobiliary | 8 (2.5) | 6 (2.6) |  |
 Central nervous | 7 (2.2) | 5 (2.2) |  |
 Cardiovascular | 6 (1.9) | 5 (2.2) |  |
 Skin and soft tissue | 4 (1.3) | 3 (1.3) |  |
 Other sites | 11 (3.5) | 8 (3.5) |  |
 Unknown | 8 (2.5) | 6 (2.6) |  |
SOFA score, mean ± SEM | 7.8 ± 0.4 | 8.0 ± 0.4 | 0.425 |
Septic shock, no. (%) | 135 (42.6%) | 108 (46.8%) | 0.232 |
Disposition in ED, no (%) | |||
 Intensive care unit admission | 107 (33.8) | 75 (32.5) | 0.417 |
 General ward admission | 116 (36.6) | 83 (35.9) |  |
 Death in ED | 15 (4.7) | 11 (4.8) |  |
 Others | 79 (24.9) | 62 (26.8) |  |
Length of stay (days), median (IQR) | 9 (4-13) | 10 (4-18) | 0.436 |
Length of antibiotics (days), median | 8 (3-13) | 9 (4-16) | 0.361 |
Compliance with recommendations, no. (%) | 85 (26.8) | 122 (52.8) | <0.001 |
 Broad-spectrum antibiotics ≤3 hours | 185 (58.4) | 160 (69.3) | 0.02 |
 Blood culture before antibiotics | 247 (77.9) | 198 (85.7) | 0.04 |
 Appropriate fluid resuscitation | 215 (67.8) | 167 (72.3) | 0.206 |
 Lactate measurement ≥2 within 6 hours | 116 (36.6) | 205 (88.7) | <0.001 |
Time to 1st antibiotics (min), median (IQR) | 121 (72-188) | 112 (68-180) | 0.349 |
7-day mortality, no (%) | 44 (13.9) | 30 (13.0) | 0.315 |
14-day mortality, no (%) | 87 (27.4) | 62 (26.8) | 0.412 |
28-day mortality, no (%) | 118 (37.2) | 74 (32.0) | 0.08 |