Fig. 1
From: Resistin directly inhibits bacterial killing in neutrophils
Comparison of bacterial killing of P. aeruginosa by PMN (neutrophils), macrophages, and monocytes in the presence of a cytochalasin B and b human resistin. Cytochalasin B significantly impaired the ability of all cell types to kill P. aeruginosa (P < 0.001 for PMN, P = 0.002 for macrophages, P < 0.001 for monocytes), underlying the importance of F-actin in the bactericidal process. Resistin significantly impaired bacterial killing of P. aeruginosa in neutrophils (P < 0.001) and macrophages (P < 0.001) but not in monocytes (P > 0.99). n = 18 (PMN), 9 (macrophages), and 16 (monocytes). Statistically significant differences in bacterial killing capacity between different cell types to each stimulant are denoted by P values on the graph. Asterisk denotes statistical significance (P < 0.05)