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Table 1 Summary of the clinical tests used in the assessment of respiratory muscle strength [63]

From: Ventilator-induced diaphragm dysfunction: translational mechanisms lead to therapeutical alternatives in the critically ill

 

Test

Threshold values

Advantages

Disadvantages

Volitional Tests

Maximum static inspiratory pressure (PImax)

Male < − 45 cm H2O

Female < − 30 cm H2O

Easy to perform.

Normal values are available

Difficult interpretation.

Lack of specificity

Maximum static transdiaphragmatic pressure (PI,di,max)

Male < 40 cm H2O (2)

Female < 30 cm H2O

Easy to perform. Well tolerated by patients.

Wide normal range.

Limited usefulness in clinical practice.

Limited normal data

Sniff transdiaphragmatic pressure (Sniff Pdi)

Male < 100 cm H2O (2)

Female < 70 cm H2O

Requires little practice. It is relatively reproducible.

Range of normal values

Technical limitations

Variability.

Maximum sniff pressures (nasal)

Male < 50 cm H2O

Female < 45 cm H2O

Maximum cough pressure

Male < 130 cm H2O

Female < 95 cm H2O

Normal ranges available

Limited validation in critically ill patient.

Nonvolitional tests

Twitch transdiaphragmatic pressure (PdiTw)

Male and female < 18 cm H2O

Measurement specific for the diaphragm and is not influenced by the central nervous system

Requires considerable skill.

Uncomfortable for patients

Diaphragm excursion (DE)

< 10 cm

Provides both morphological and functional information in real time. Allows repeated measurements over time and monitoring recovery

Learning curve.

Inter-observer variations.

Availability.

Reproducibility

Inspiratory diaphragm thickening fraction (TFdi)

< 20%