Table 1 Physiological variables, norepinephrine dose and blood count during the experiment

 − 24

71 (± 6)

76 (± 13)

 − 22

84 (± 6)

75 (± 11)

 − 18

74 (± 9)

80 (± 14)

 0

78 (± 11)

74 (± 9)

85 (± 10)

 1

77 (± 10)

78 (± 8)*

80 (± 5)

 2

77 (± 13)

91 (± 6)*

87 (± 30)

 3

69 (± 11)

92 (± 7)*

95 (± 24)

 4

81 (± 11)

92 (± 8)

94 (± 19)

 5

76 (± 9)

88 (± 7)

77 (± 6)

 6

75 (± 9)

86 (± 7)

63 (± 9)

 − 24

0 (0–0)

0 (0–0.07)

 − 22

0 (0–0)

0 (0–0.07)

 − 18

0 (0–0)

0.06 (0–0.07)

 0

0 (0–0)

0 (0–0)

0.06 (0–0.29)

 1

0.06 (0–0.13)

0 (0–0)

0.26 (0.1–0.29)*

 2

0.03 (0–0.13)

0 (0–0)

0.26 (0–0.58)

 3

0.19 (0–0.28)

0 (0–0)*

0.26 (0–0.58)

 4

0.13 (0.06–0.51)

0 (0–0)

0.26 (0–0.58)

 5

0.13 (0.06–0.26)

0 (0–0)

0.26 (0–0.58)

 6

0.13 (0.06–0.14)

0 (0–0)

0.26 (0–0.58)

 − 24

2.7 (± 0.5)

3.2 (± 0.2)

 − 22

2.9 (± 0.4)

2.6 (± 0.3)

 − 18

3.0 (± 0.6)

2.6 (± 0.6)

 0

2.9 (± 0.9)

3.8 (± 0.6)

3.0 (± 0.4)

 1

2.2 (± 0.4)

4.3 (± 0.5)***

2.7 (± 0.4)

 2

2.7 (± 1.2)

3.6 (± 0.7)***

3.5 (± 0.6)

 3

2.0 (± 0.2)

3.6 (± 0.7)***

3.6 (± 1.0)

 4

2.0 (± 0.5)

4.0 (± 0.7)

3.6 (± 0.7)

 5

2.2 (± 0.5)

3.8 (± 0.8)

4.0 (± 0.7)

 6

2.5 (± 0.2)

4.4 (± 0.7)

4.4 (± 0.9)

 − 24

1.8 (± 0.26)

1.1 (± 0.38)

 − 22

1.2 (± 0.21)

0.7 (± 0.19)

 − 18

0.8 (± 0.13)

0.7 (± 0.16)

 0

1.2 (± 0.37)

0.8 (± 0.16)

0.8 (± 0.11)

 1

2.2 (± 0.82)

1.0 (± 0.10)***

1.4 (± 1.9)

 2

2.2 (± 0.27)

1.2 (± 0.21)***

1.9 (± 0.56)

 3

3.0 (± 0.69)

1.1 (± 0.29)***

2.4 (± 0.32)

 4

2.6 (± 1.2)

1.1 (± 0.34)

1.8 (± 0.81)

 5

2.0 (± 1.2)

1.0 (± 0.27)

1.5 (± 0.76)

 6

1.4 (± 1.1)

0.9 (± 0.19)

1.3 (± 0.81)