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Intensive Care Medicine Experimental
Fig. 4 | Intensive Care Medicine Experimental

Fig. 4

From: Increased mortality in elderly patients with acute respiratory distress syndrome is not explained by host response

Fig. 4

Mediation analysis. a, b Tissue plasminogen activator is a mediator which partially explains the association between age and mortality. *Adjusted for ethnic background, gender, admission type, readmission, direct hit for ARDS, Charlson Comorbidity Index, APACHE-IV score adjusted for age, immunodeficiency, tidal volume per predicted body weight, and positive end-expiratory pressure. ADE, average direct effect; ACME, average causal mediation effect. A p value < 0.05 was considered as statistical significant

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