Skip to main content

Table 1 Respiratory mechanics

From: Increased effort during partial ventilatory support is not associated with lung damage in experimental acute lung injury

 

PC (n = 9)

AC (n = 10)

PS100 (n = 9)

PS60 (n = 10)

PS20 (n = 10)

Main effect

Within group

Between group

PAW [cmH2O]

BL

15 ± 3

15 ± 4

13 ± 2

14 ± 3

13 ± 1

  

ALI-BL

22 ± 4

22 ± 4

18 ± 3

20 ± 4

21 ± 1

  

ALI-End

26 ± 6#*

25 ± 7

19 ± 7

15 ± 5*

9 ± 3#*

0.060

0.000

PTPinsp [cmH2O]

BL

16 ± 4

15 ± 4

13 ± 4

14 ± 4

13 ± 5

  

ALI-BL

22 ± 5

23 ± 4

20 ± 6

19 ± 6

19 ± 4

  

ALI-End

25 ± 7

26 ± 7

24 ± 9

23 ± 6

23 ± 8

0.006

0.987

PTPexp [cmH2O]

BL

5 ± 3

4 ± 2

4 ± 3

6 ± 2

4 ± 4

  

ALI-BL

4 ± 3

5 ± 2

6 ± 5

4 ± 3

3 ± 3

  

ALI-End

5 ± 4

5 ± 4

6 ± 4

4 ± 2

3 ± 6

0.790

0.337

VT [ml/kg BW]

BL

9.6 ± 1.2

8.7 ± 0.8

8.7 ± 0.6

8.8 ± 1

8.6 ± 0.9

  

ALI-BL

8.4 ± 1.6

9.4 ± 2.0

8.9 ± 2.8

11 ± 4

8.6 ± 1.9

  

ALI-End

9.0 ± 1.2

9.0 ± 1.2

9.1 ± 1.0

10 ± 3

8.9 ± 1.2

0.919

0.853

RR [min−1]

BL

77 ± 18

81 ± 15

84 ± 8

87 ± 7

85 ± 9

  

ALI-BL

75 ± 17

82 ± 14

85 ± 11

92 ± 6

84 ± 11

  

ALI-End

86 ± 16#

94 ± 17#

71 ± 31

77 ± 17#

80 ± 20

0.213

0.011

VE [ml/min]

BL

334 ± 115

328 ± 68

348 ± 42

353 ± 56

339 ± 48

  

ALI-BL

323 ± 60

346 ± 86

364 ± 82

403 ± 91

352 ± 58

  

ALI-End

318 ± 70

411 ± 117

320 ± 115

396 ± 123

330 ± 130

0.662

0.345

  1. BL baseline measurement on pressure controlled ventilation, ALI-BL measurement on pressure-controlled ventilation after induction of lung injury, ALI-End last measurement after 2–4 h of experimental ventilation mode, PAW peak airway pressure, PTPi peak inspiratory transpulmonary pressure, VT tidal volume, RR respiratory rate, VE minute ventilation, *p < 0.05 vs. other groups #p < 0.05 vs. ALI-BL