Aortic volume determines global end-diastolic volume measured by transpulmonary thermodilution

Intensive Care Medicine Experimental

Table 4 Statistical significance of confounding variables for GEDV

Statistical model	(1) Basic model: biometric descriptors	(2) Basic model + V. cava	(3) Basic model + aorta	(4) Basic model + aorta + V. cava
Age	p < 0.001	p < 0.001	p > 0.05	p > 0.05
Male sex	p > 0.05	p > 0.05	p > 0.05	p > 0.05
Height	p > 0.05	p > 0.05	p > 0.05	p > 0.05
Weight	p = 0.003	p = 0.002	p > 0.05	p > 0.05
Aortic volume			p < 0.001	p < 0.001
Vena cava volume		p = 0.003		p = 0.009
Explained variance	38%	48%	59%	64%
Difference to previous model		p < 0.001	p < 0.001	p < 0.001

Multivariate statistical models investigate (1) the dependence of GEDV values on age, male sex, height, and body weight (basic model); (2) the biometric parameters from the basic model and additionally the volume of the vena cava; (3) the parameters from the basic model and additionally the aortic volume; and (4) the parameters from the basic model with biometric descriptors and both vena cava volume and aortic volume. Values in italics indicate significance