Table 4 Haemodynamics during Impella CP going from minimum to moderate norepinephrine
Impella CP+minimally required NE, n = 8 | Impella CP + moderate NE, n = 8 | p value | |
|---|---|---|---|
NE dose, μg/kg/min, median (range) | 0.03 (0.00–0.10) | 0.1 (0.10–0.18) | |
Svo2, %, mean (SD) | 54 (12) | 70 (15) | <0.001 |
Cardiac output, L/min, mean (SD) | 4.4 (0.9) | 5.5 (0.9) | 0.01 |
MAP, mmHg, median (Q1, Q3) | 61 (58, 63) | 64 (60, 75) | 0.08 |
Heart rate, bpm, median (Q1, Q3) | 77 (70, 82) | 98 (89, 111) | 0.01 |
PAPsystolic, mmHg, median (Q1, Q3) | 31 (24, 36) | 42 (37, 43) | 0.01 |
PAPdiastolic, mmHg, mean (SD) | 19 (4) | 22 (6) | 0.03 |
PAPmean, mmHg, median (Q1, Q3) | 25 (20, 29) | 30 (29, 34) | 0.01 |
CVP, mmHg, mean (SD) | 12 (4) | 11 (4) | 0.04 |