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Table 1 Schedule of interventions and assessments

From: A functional observational battery for evaluation of neurological outcomes in a rat model of acute bacterial meningitis

Time point

 

Day 0

Day 1

Day 2

 

Day 6

0 h

24 h

36 h

48 h

60 h

*

144 h

Infect

Treat and assess

Close-out

Preparatory surgery and infection

X

      

Interventions

 Penicillin G + betamethasone

 

X

X

X

X

*

 

Assessments

 Weight

X

X

X

X

X

*

X

 Temperature

X

X

 

X

  

X

 Functional observational battery

 

X

 

X

  

X

Sample collection

 CSF

 

X

 

X

  

X

 Brain

      

X

  1. *Every 12 h thereafter until close-out