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Table 2 Main characteristics of patients with hypoxemia classified 24 h after onset of hypoxemia

From: Prognostic classification based on P/F and PEEP in invasively ventilated ICU patients with hypoxemia—insights from the MARS study

Characteristics

Group I, n = 296

Group II, n = 96

Group III, n = 177

Group IV, n = 120

P value

APACHE IV score, median [IQR]

76 [59–97]

77 [60–97]

80 [62–98]

85.5 [62–111]

0.06

Age, median [IQR]

62 [49–70]

62 [50–72]

64 [54–72]

62 [53–72]

0.26

Gender, male, n (%)

183 (62)

62 (65)

116 (66)

80 (67)

0.74

Ventilation parameters, median [IQR]

 Maximum airway pressure, cm H2O

16 [13–19]

21 [18–24]

16 [13–20]

22 [19–27]

< 0.01

 PEEP, cm H2O

5 [5–5]

8 [6–8]

5 [5–5]

8 [7–10]

< 0.01

 FiO2, %

40 [35–41]

40 [40–41]

40 [40–41]

41 [40–50]

< 0.01

 PaO2/FiO2, mmHg

303 [280–353]

294 [267–339]

212 [190–233]

211 [165–226]

< 0.01

 Tidal volume, ml/kg PBW

7.3 [6.4–8.5]

7.3 [6.3–8.4]

7.3 [6.4–8.6]

7.3 [6.5–9]

0.87

 Respiratory rate, per minute

17 [14–22]

18 [15–21]

19 [15–23]

18 [15–24]

0.15

 PaO2, mmHg

120 [105–144]

126 [111–155]

90 [78–98]

94 [82–103]

< 0.01

 PaCO2, mmHg

39 [35–44]

41 [36–45]

42 [37–48]

41 [36–48]

0.01

  1. APACHE acute physiology and chronic health evaluation, IQR interquartile range, PBW predicted body weight, PEEP positive end–expiratory pressure